Editorial: Bioengineering and Metabolism

Editorial: Circadian Rhythms and Metabolism

Editorial: Drug Metabolism and Toxicology

A drug metabolism study is an important aspect of the early drug discovery and development process [1,2]. In order to improve the understanding of drug efficacy and safety characteristics, it is desirable to investigate the drug metabolism in animals or humans [3,4]. These metabolism studies involve metabolic stability, cytochrome P-450 (CYP-450) induction or inhibition and metabolite identific...

Holistic bioengineering: rewiring central metabolism for enhanced bioproduction

What does it take to convert a living organism into a truly productive biofactory? Apart from optimizing biosynthesis pathways as standalone units, a successful bioengineering approach must bend the endogenous metabolic network of the host, and especially its central metabolism, to support the bioproduction process. In practice, this usually involves three complementary strategies which include...

Editorial: Control of Adipocyte Differentiation and Metabolism

For many years, adipose tissue was considered a passive tissue with the only function of storing excess energy as triglycerides and releasing fatty acids according to necessity. Now it becomes increasingly clear that adipose tissue is an endocrine organ that plays a critical role in modulating energy expenditure and homeostasis. White adipose tissue is thus responsible for the secretion of an a...

Bioengineering

While the bacteriocin Nisin has been employed by the food industry for 60 y, it remains the only bacteriocin to be extensively employed as a food preservative. This is despite the fact that the activity of Nisin against several food spoilage and pathogenic bacteria is poor and the availability of many other bacteriocins with significant potential in this regard. An alternative route to address ...